FASCINATION ABOUT ILOKAASU KäRKKäINEN

The last proposed mechanism of RBC vasodilation within the existence of nitrite is the reduction of nitrite to NO by Hb. Brooks 1st analyzed the nitrite Hb interaction in 1937 which work was later prolonged by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to form metHb and NO (Brooks, 1937; Doyle et al., 1981